to make someone feel confused Anglais:

They were perplexed by her response.

I must acknowledge that, although it is not typical of the Presidency to say so, I am closing it with a degree of perplexity.

To perplex is defined as to confuse or complicate.

An example of perplex is to challenge a class with a very difficult question.

I was perplexed as to my own best course of action.